Intermittent fasting reduces Multiple Sclerosis (MS)-like symptoms, a study
on mice by U.S. researchers shows.
MS is a potentially disabling disease of the brain and spinal cord (central nervous system)
In the study, mice were either allowed to eat freely or fed every other day for four weeks before receiving
an immunization to trigger MS-like symptoms.
Both groups of mice then continued on their same diets for another seven weeks.
The mice that fasted every other day were less likely to develop signs of neurological damage such as difficulty
walking, limb weakness and paralysis.
Some of the fasting mice did develop MS-like symptoms, but they appeared later and were less severe than in the
mice that ate their fill every day.
In addition, the fasting mice’s immune systems seemed to be dialed down.
As compared with mice that took daily meals, those that ate every other day had fewer pro-inflammatory immune
cells and more of a kind of immune cell that keeps the immune response in check.
“There are several possible ways fasting can affect inflammation and the immune response,” said Laura Piccio,
an associate professor of neurology at Washington University School of Medicine in St. Louis.
“One is by changing hormone levels. We found that levels of the anti-inflammatory hormone corticosterone were
nearly twice as high in the fasting mice.”
The researchers said fasting also could act through the gut microbiome. A change in the makeup of
the gut community could alter whether the immune system has a pro- or anti-inflammatory bent.
After four weeks, the mice that fasted sheltered a more diverse ecosystem in their guts than mice that ate
In particular, the fasting mice had more of the soothing probiotic bacteria Lactobacillus, which
other studies in mice have linked to milder MS-like symptoms.
Moreover, transferring gut bacteria from fasting mice to non-fasting mice made the recipients less susceptible
to developing MS-like symptoms, suggesting that something in the microbial community was protecting the mice.
Based on this mice study that was published earlier June in the journal Cell Metabolism, the researchers
at the university are now recruiting human patients with relapsing-remitting MS for a 12-week study.
All rights reserved. This material, and other digital content on this website, may not be reproduced, published, broadcast, rewritten or redistributed in whole or in part without prior express written permission from LEADERSHIP Nigeria Newspapers. Contact: email@example.com
- OPINION21 hours ago
Buhari: Workers’ New Bride
- NEWS18 hours ago
Kogi Govt Commences Payment Of 4 Months’ Salary To Workers
- NEWS11 hours ago
2019: Why I Choose Balarabe As My Running Mate – el-Rufai
- NEWS15 hours ago
FG Signs MoU To Take Over Farin Ruwa Dam Project
- CRIME12 hours ago
Teenage Female Suicide Bomber Arrested In Borno
- NEWS14 hours ago
Drama In Court! Woman Makes U-Turn On Divorce, Begs For Mercy
- BUSINESS24 hours ago
Diamond Bank Denies Acquisition Talks With Access Bank
- NEWS14 hours ago
Senior Civil Servants Pleaded For New Wage Before Year End