Eric Dane, ‘Grey’s Anatomy’ Star, Dies At 53 After ALS Battle

Actor Eric Dane, best known for his roles in Grey’s Anatomy and Euphoria, has died at the age of 53 following a battle with Amyotrophic Lateral Sclerosis (ALS). His family confirmed the news in a statement, saying he passed away surrounded by loved ones after months of advocating for awareness about the neurodegenerative condition.

Dane rose to global recognition as Dr Mark Sloan, popularly known as “Dr McSteamy,” on Grey’s Anatomy, a role that cemented his status as one of television’s most recognisable faces. He later gained renewed acclaim portraying Cal Jacobs in HBO’s Euphoria, showcasing a darker, more complex side of his acting range.

The California-born actor publicly revealed his ALS diagnosis in April 2025 and used his platform to highlight the challenges faced by people living with the condition. ALS, a progressive illness that affects nerve cells, is associated with recognisable faces. He later gained renewed acclaim portraying Cal Jacobs in HBO’s Euphoria, showcasing a darker, more complex side of his acting range.

The California-born actor publicly revealed his ALS diagnosis in April 2025 and used his platform to highlight the challenges faced by people living with the condition. ALS, a progressive illness that affects nerve cells controlling muscle movement, gradually limits mobility and speech.

Beyond his medical drama fame, Dane appeared in series such as Charmed and The Last Ship, as well as in films such as Marley & Me, Valentine’s Day, and Burlesque. Colleagues and friends across the entertainment industry have since shared tributes, remembering him for his warmth, humour and dedication to his craft.